Hello, Kosmos has multi-location solutions for LightSpeed Retail and Shopify right now. See landing page and video here.
You can sync all your individual store locations to each Shopify Location. So, each SKU will have a location assigned to it.
We are also in the final stages of launching a solution for WooCommerce locations & LightSpeed Retail too. This should be out in the next 30 to 45 days.
BigCommerce is also launching a locations solution, just like Shopify and we're already part of the partner beta program and are currently evaluating the BigCommerce API for Multi-Locations right now.
If you have any questions, feel free to contact us at the link above.